The below diagram illustrates the Asynchronous service workload on this scenario:
On the above diagram the bottleneck it's on the Sales Organization taking 59% of the Asynchronous processing time delaying the execution of the IT staff Organization workflows.
To avoid these type of bottlenecks we can limit the number of system jobs the Async service picks up per organization by setting the AsyncSelectMaxItems with the following PowerShell commands:
add-pssnapin Microsoft.Crm.Powershell
$itemSetting = new-object 'System.Collections.Generic.KeyValuePair[String,Object]'("AsyncSelectMaxItems",100)
$configEntity = New-Object "Microsoft.Xrm.Sdk.Deployment.ConfigurationEntity"
$configEntity.LogicalName="Deployment"
$configEntity.Attributes = New-Object "Microsoft.Xrm.Sdk.Deployment.AttributeCollection"
$configEntity.Attributes.Add($itemSetting)
Set-CrmAdvancedSetting -Entity $configEntity
The following diagram illustrates how the asynchronous service would balance the system jobs per organization: